Tall BP may increase bone tissue the aging process, claims research : The Tribune Asia - Upsmag - Magazine News


Tall BP may increase bone tissue the aging process, claims research : The Tribune Asia

New York, September 8

A group of scientists has unearthed that raised blood pressure can result in bone tissue loss and bone that is osteoporosis-related.

In lab studies on rats, they found that when compared to the mice that are young high blood pressure, the young mice with induced high blood pressure had a substantial 24 percent lowering of bone tissue amount small fraction.

They also end from an 18 percent lowering of the depth for the sponge-like bone that is trabecular at the end of long bones, such as femurs and the spinal column, and a 34 per cent reduction in estimated failure force, which is the ability of bones to withstand different types of force.

“In contrast, the older mice who were given the infusion that is angiotensin-II maybe not show similar bone tissue loss.

High hypertension and weakening of bones are typical conditions people that are affecting some can have both simultaneously.

“Bone marrow is where both bone that is new new resistant cells are manufactured. We suspect that more immune that is pro-inflammatory in the bone marrow may be leading to damage of the bone and making it weaker,” said Elizabeth Maria Hennen, from Vanderbilt University in Nashville, Tennessee, the US.

“By understanding how hypertension contributes to osteoporosis, we may be able to reduce the risk of osteoporosis and better protect people later in life from having fragility fractures and a lower quality of life,” she added.

The researchers compared young mice (equivalent human age 20-30) with induced hypertension to older mice (equivalent human age 47-56) without hypertension to understand the relationship between hypertension and bone aging, according to the study presented in American Heart Association’s Hypertension Scientific Sessions 2022 conference.

“Twelve young rats and 11 older rats were given angiotensin II– a hormone that leads to blood that is high for six months,” the scientists said.

“Two other control sets of 13 young mice and 9 old mice received a buffer solution that would not consist of angiotensin II, and these mice would not develop blood that is high,” they added After six weeks, the bones of rats from all four groups were analyzed using micro-computed tomography, an advanced imaging technique.

IANS

New York, September 8

A team of researchers has discovered that high blood pressure may lead to bone loss and bone that is osteoporosis-related.

In lab studies on rats, they discovered that in comparison to the mice that are young hypertension, the young mice with induced hypertension had a significant 24 per cent reduction in bone volume fraction.

They also end from an 18 per cent reduction in the thickness of the sponge-like bone that is trabecular at the conclusion of long bones, such as for example femurs additionally the spine, and a 34 % lowering of estimated failure force, which can be the power of bones to withstand various kinds of force.

“In comparison, the older mice have been offered the infusion that is angiotensin-II not exhibit similar bone loss.

High blood pressure and osteoporosis are common diseases people that are affecting some may have both simultaneously.

“Bone marrow is where both bone that is new new immune cells are produced. We suspect that more immune that is pro-inflammatory in the bone tissue marrow could be causing harm for the bone tissue and rendering it weaker,” said Elizabeth Maria Hennen, from Vanderbilt University in Nashville, Tennessee, the US.

“By focusing on how high blood pressure plays a part in weakening of bones, we possibly may have the ability to decrease the danger of weakening of bones and better protect people later on in life from having fragility fractures and a lesser standard of living,” she added.

The scientists contrasted young mice (comparable human age 20-30) with induced high blood pressure to older mice (comparable human age 47-56) without high blood pressure to comprehend the connection between high blood pressure and bone aging, according to your study offered in American Heart Association’s Hypertension Scientific Sessions 2022 seminar.

“Twelve young rats and 11 older rats received angiotensin II– a hormone leading to blood that is high for six weeks,” the researchers said.

“Two other control groups of 13 young mice and 9 old mice received a buffer solution that did not include angiotensin II, and these mice did not develop blood that is high,” they included After six months, the bones of rats from all four teams had been analyzed making use of micro-computed tomography, an enhanced imaging strategy.

IANS

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